Opinion Paper

Gli inositoli nella sindrome dell’ovaio policistico: evidenze cliniche e razionale d’impiego
S.Salomone, M.Carrubba, F.Drago
The role of Inositols in PCOS – Opinion Paper
Giovanni Scambia, Stefano Lello, Salvatore Salomone, Luigi Fedele, Anna Capozzi, Franca Fruzzetti, Costantino Di Carlo, Maria Angela Sortino, Filippo Drago
Polycystic Ovary Syndrome: Insights into the Therapeutic Approach with Inositols
Maria A. Sortino, Salvatore Salomone, Michele O. Carruba and Filippo Drago

STUDIES on DCI’s mechanims and functions

Studies on D-Chiro-Inositolo and PCOS

Ovulatory and metabolic effects of D-Chiro-Inositol in the PCOS
Nestler JE, Jakubowicz DJ, Reamer P, Gunn RD, Allan G.
Modulatory role of D-chiro-inositol and alpha lipoic acid combination on hormonal and metabolic parameters of overweight/obese PCOS patients. 
Alessandro D. Genazzani, Alessia Prati, Tommaso Simoncini, Antonella Napolitano
D-chiro-Inositol and alpha lipoic acid treatment of metabolic and menses disorders in women with PCOS
Cianci A, Panella M, Fichera M, Falduzzi C, Bartolo M, Caruso S
Evaluation of ovarian function and metabolic factors in women affected by polycystic ovary syndrome after treatment with d-Chiro-Inositol
Antonio Simone Laganà, Luisa Barbaro & Alfonsa Pizzo
Evaluation of the treatment with d-chiroinositol on levels of oxidative stress in pcos patients
De Leo V, La Marca A, Cappelli V, Stendardi A, Focarelli R, Musacchio MC, Piomboni P.
Protein modification as oxidative stress marker in follicular fluid from women with polycystic ovary syndrome: the effect of inositol and metformin
Piomboni, P., Focarelli, R., Capaldo, A., et al.
The menstrual cycle regularization following D-chiro-inositol treatment in PCOS women: a retrospective study
Antonio La Marca, Valentina Grisendi, Giulia Dondi, Giovanna Sighinolfi, and Antonio Cianci
Modulation of gonadotrophin induced steroidogenic enzymes in granulosa cells by d-chiroinositol
Sacchi, S., Marinaro, F., Tondelli, D., Lui, J., Xella, S., Marsella, T., Tagliasacchi, D. et al.
Modulatory role of D-chiro-inositol (DCI) on LH and insulin secretion in obese PCOS patients
Sacchi, S., Marinaro, F., Tondelli, D., Lui, J., Xella, S., Marsella, T., Tagliasacchi, D. et al.

STUDIES ON D-CHIRO-INOSITOL, DIABETES AND GESTATIONAL DIABETES

Both myo-inositol to chiro-inositol epimerase activities and chiro-inositol to myo-inositol ratios are decreased in tissues of GK type 2 diabetic rats compared to Wistar controls
Sun TH1, Heimark DB, Nguygen T, Nadler JL, Larner J.
D-Chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects
I Asplin, G Galasko, and J Larner
Synergistic Effects of d-Chiro-Inositol and Manganese on Blood Glucose and Body Weight of Streptozotocin-Induced Diabetic Rats
Gilbert Gluck, Tatiana Anguelova1, Douglas Heimark2 and Joseph Larner
Metformin Therapy Increases Insulin-Stimulated Release od D-Chiro-Inositol-Containing Inositolphospoglycan Mediator in Woman with Polycystic Ovary Sindromeents
Jean-Patrice Baillargeon, Maria J. Iuorno, Daniela J. Jakubowicz, Teimuraz Apridonidze, Na He and John E. Nestler
Pioglitazone Therapy Increases Insulin-Stimulated Release of D-Chiro-Inositol-Containing
Anshu Gupta, Daniela Jakubowicz and John E Nestler
A pilot study of d-chiro-inositol plus folic acid in overweight patients with type 1 diabetes
Anna Rita Maurizi, Marika Menduni, Rossella Del Toro, Shadi Kyanvash, Daria Maggi, Chiara Guglielmi, Angelo Lauria Pantano, et al.
Ruolo del D-chiro-inositolo nelle alterazioni del metabolismo glucidico in gravidanza
D. Costantino, C. Guaraldi
The Effectiveness of D-Chiro Inositol Treatment in Gestational Diabetes
Nicolina Di Biase et al.
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